This article explains why vacuum changes the conditions inside a fluid bed dryer, why standard airflow-driven fluidization breaks down at low pressure, and why vibration takes over as the fluidizing mechanism in a vacuum fluid bed dryer.
Lowering the pressure inside a dryer lowers the boiling point of water and solvents, so moisture evaporates at a much lower temperature than it would at atmospheric pressure. That single change protects heat-sensitive materials from thermal degradation and reduces the oxygen available to react with the material during drying, which matters for materials prone to oxidation.
Fluidization normally depends on the drag force from airflow overcoming gravity and interparticle forces, and that drag force depends on gas density as well as velocity. Under vacuum, gas density drops sharply, so there simply isn't enough gas mass moving through the bed to generate the drag force needed to suspend particles, no matter how high the velocity is pushed.
Because airflow can't reliably do the job under vacuum, vibration takes over as the main force keeping particles in motion, rather than acting as a supplement to airflow the way it does at atmospheric pressure. This is why a "vacuum fluid bed dryer" in practice is almost always a vibrating vacuum dryer: vacuum sets the drying atmosphere, while vibration handles the actual particle motion that airflow can no longer provide.
Vacuum operation fits materials that degrade, discolor, or lose activity at the temperatures atmospheric drying would require, and materials where oxidation during drying is a quality risk rather than a cosmetic one. It's also the practical choice when a process needs to recover solvent rather than vent it, since a sealed vacuum system can capture and condense solvent vapor instead of releasing it with exhaust air.
Vacuum drying typically takes longer per batch than airflow-driven drying, since removing the convective heat that hot air would normally provide means heat has to reach the material some other way, usually through a heated jacket or internal heating panels rather than the air itself. Confirming that the equipment can supply enough heat through direct contact, not just enough vacuum, is what determines whether the process actually dries the batch in a reasonable time.
Vacuum fluid bed drying lowers the temperature and oxygen exposure a material sees during drying, but it removes airflow's ability to fluidize the bed in the process. Vibration fills that gap, which is why vacuum and vibration are paired rather than treated as separate options for materials that need both a controlled atmosphere and reliable particle motion.
The following article introduces recommended vibrating dryers by industry.



*1 from official Website (https://www.v-dryer.jp/dryingtest.html)
*2 Related to contact with food and dairy products.